22nd Infantry Regiment completed its organization at Camp Trenton, Tennessee, in August, 1861. Men of this unit were recruited in Memphis and Hardeman, Carroll, Gibson, and Dyer counties. It served in Cheatham's, R.M. Russell's, and B.R. Johnson's Brigade, and saw action in the conflicts at Belmont and Shiloh. On June 16, 1862, it merged into the 12th Regiment. The field officers were Colonels Thomas J. Freeman and Lipscomb P. McMurry; Lieutenant Colonels M.H. Pirtle, A.T. Robertson, and Francis M. Stewart; and Major Benjamin T. Davis.