Organized at Louisiana, Mo., for six months September, 1861. Guard bridges in Franklin County September, 1861. Duty at Troy, Louisiana, Ashley, Wellsville and Bowling Green until February, 1862. Mustered out February 5, 1862.

Called into service September 25, 1864, to repel Price's invasion of Missouri. Relieved from active service October 31, 1864.

Duty at Sedalia, Mo. Scout from Salem to Sinking Creek, Salem River, April 18-21, 1863. Operations against Quantrell in his raid into Kansas August 20-28, 1863. Big Creek, near Pleasant Hill, August 22. Near Hopewell August 25-26. Operations against Shelby September 22-October 26. Tipton and Syracuse October 10 (Cos. "D" and "E"). Booneville October 10-11 (Cos. "D" and "E"). Merrill's Crossing and Dug Ford, near Jonesborough, October 12 (Cos. "D" and "E"). Marshall October 13 (Cos. "D" and "E"). Johnston October 16. Cedar County October 17. About Honey Creek October 19 (Detachment).

Called into service September 25, 1864, to repel Price's invasion of Missouri. Relieved from active service October 31, 1864.

Duty at Springfield, Mo., and in the District of Southwest Missouri, operating against guerrillas. Bloomfield, Mo., January 27, 1863. Scout on Bennett's Bayou and skirmishes August 23, 1863 (Co. "H"). Operations against Shelby September 22-October 26. Scout from Houston to Jack's Fork November 4-9, 1863 (Detachment). Scouts from Houston December 9-19. Ordered from Springfield to Rolling Prairie February 6, 1864. Duty in Christian, Douglass, Wright, Dade and Stone Counties until July, 1864. Scout from Yellville to Buffalo River March 13-26. Operations in Southwest Missouri July 18-23 and August 1-28. Skirmish Polk County August 28. Operations against Price's invasion of Missouri September to November. Attached to 3rd Brigade, Cavalry Division, Dept. of Missouri. Moreau Creek October 7. Russellville October 9. California October 9. Near Booneville October 11-12. Little Blue October 21. Independence, Big Blue and State Line October 22. Big Blue and Westport October 23. Little Osage, Mine Creek and Marias des Cygnes October 25. Battle of the Marmiton (or Charlot) October 25. Newtonia October 28. Designation changed to 16th Missouri Cavalry November 1, 1864.

Called into service to repel Price's invasion of Missouri September 25, 1864. Relieved from active service October 31, 1864.

Duty at Springfield, Mo., and other points in District of Southwest Missouri. Action at Bloomfield, Mo., January 17, 1863. Dade County July 24, 1863 (Co. "E"). Scout from Greenfield September 15-18. Operations against Shelby September 22-October 26. Oregon (or Bowers' Mill) October 4. Greenfield October 5. Stockton October 5 (Detachment). Operations in Northern Arkansas December, 1863, to February, 1864. Duty in Christian, Douglass and Stone Counties until July. Scouts near Neosho and Carthage May 18-23. At Mt. Vernon May. Skirmish near White Hare June 15. Scout from Mt. Vernon June 19-25. Operations in Southwest Missouri July 18-23 and August 1-28. Skirmish Polk County August 28. Operations against Price's invasion of Missouri September to November. Attached to 3rd Brigade, Cavalry Division, Dept. of Missouri. Moreau Creek October 7. Russellville October 9. California October 9. Near Booneville October 11-12. Little Blue October 21. Independence, Big Blue and State Line October 22. Big Blue and Westport October 23. Little Osage and Mine Creek, Marias des Cygnes, October 25. Engagement on the Marmiton (or Battle of Chariot) October 25. Newtonia October 28. Designated 15th Missouri Cavalry November 1, 1864.

Operations against Shelby September 22-October 26, 1863. Booneville October 11-12. Merrill's Crossing, Dug Ford, near Julesborough October 12. Marshall October 13. Mustered out November, 1863.

Called into service September 25, 1864, to repel Price's invasion of Missouri. Relieved from active service October 31, 1864.